The U.S. market for substance abuse treatment and diagnosis exceeds $3.1 billion annually, yet no effective drug treatment for alcoholism has been discovered that significantly reduces alcohol consumption.
Researchers have re-purposed the use of an FDA approved antibiotic currently available in the market that significantly reduces alcohol consumption in patients. The results of a mouse model study show a statistically significant reduction in alcohol consumption for groups treated with the described drug, with greater percent reductions expressed in males as compared to female subjects. These data suggest that the anti-consumption activity of certain antibiotic derivatives stems from an effect in the central nervous system.
Reference Number: D-1164
Features, Benefits & Advantages:
Reduce alcohol consumption and alcohol-related side effects
Advance scientific understanding of antibiotic interactions with the central nervous system
A U.S. Provisional Patent application, Serial 62/166,464 was filed on 5/26/15 for this invention.
This invention has been reduced to practice in a murine model and research continues to further develop the technology.
Susan Bergeson, Ph. D., Associate Professor, Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, Texas.
Peter Syapin, Ph. D., Professor, Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, Texas.
Keywords: alcohol consumption, antibiotics, repurpose