This technology consists of a microdevice that separates blood cells based on differences in antigen expression. Cells of the same phenotype are separated based on their activation levels during infection and resting, thus enabling the microdevice to provide differential cell counts as a diagnostic tool for infections and inflammations.
- Pharmaceuticals/Health Care
- In Vitro Diagnostics
Features, Benefits & Advantages:
- Provides differential cell counts in a short-time span
- Allows for the quick identification of infections, particularly sepsis (a time critical diagnosis)
- Implementable in any clinical setting due to ease of use and low cost
A prototype has been produced and tested. An IRB is pending approval to test human samples.
Cellular separations: a review of new challenges in analytical chemistry. Analytica chimica acta .11/2007; 601(1):26-35. DOI: 10.1016/j.aca.2007.08.0