Method of Manipulating Grape Berry Ripening by Small RNAs

Technology #d-0862

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Christopher Rock
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David McClure
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Patent Protection

US Patent Pending
Trans-acting small interfering RNA4: key to nutraceutical synthesis in grape development
PubMed, July 6, 2013

Through advanced computer modeling, genes have been discovered that control development of flavonoids in seed producing plants.  Flavonoids are involved in plant development, defense against stress, and characteristics such as color, aroma, and flavor.  Small RNAs that target these genes can be used to manipulate ripening and nutritional value, especially in grapes.

Market Applications:

• Fruit industry

• Wine industry

Features, Benefits, & Advantages:

Bioinformatic information has shown that MYBA6, MYBA7, and the 4 newly identified loci have target sites for small RNAs (TAS4-siR81(-) and miR828).  These small RNAs target sites present on transcription factors.  These transcription factors then regulate expression of genes affecting plant development or secondary metabolism biosynthesis.

• Control of plant development

• Control of berry ripening

Development Stage:

This invention has been tested and is part of an ongoing research program.