Dr. Robert Shaw

Professor Shaw's research program involves the study of the structure and function of physiologically important metalloenzymes. Structures of the metal binding sites of these biological molecules are under investigation largely through the use of optical and electron paramagnetic resonance (EPR) spectroscopy. Mechanistic details of the functions of metal ions in these proteins are being studied through the use of spectroscopy coupled to rapid kinetic techniques in order to detect short-lived species such as reaction intermediates and enzyme complexes with substrates or inhibitors. Enzyme structure-function relationships are analyzed by site-directed mutagenesis combined with presteady-state spectroscopy and steady-state enzyme kinetic techniques.

External Link (www.depts.ttu.edu)